01 / Your routine
Skin feels short on moisture
Add hydration in a fluid format before your cream, rather than adding a second rich moisturizer.
Finding your next skin conversation…
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Finding your next skin conversation…
PDRN5+ / 1.5% PDRN (Sodium DNA) / 30 mL
1.5% Sodium DNA + five-peptide blend
Hydration, in a light layer. Before your cream.
Editorial imagery · AI-generated
Current packaging · 30 mL / 1 fl oz
1.5% PDRN (Sodium DNA) and the package's five-peptide blend in a fluid serum. Add a light hydrating step for soft skin feel and a smoother-looking finish, then follow with your usual moisturizer.
The feel, in Ann’s own words.
“My skin feels soft and smooth.”
Public review excerpt · Individual experience
Read the original review ↗
Your lighter leave-on step
When you want a hydrating step before your moisturizer, reach for a serum format. This pale pink fluid spreads into a thin layer, bringing the label's Sodium DNA and peptide blend together with a moisture-supporting base.
01 / Your routine
Add hydration in a fluid format before your cream, rather than adding a second rich moisturizer.
02 / Your routine
Use the label's small dropper amount and spread one even layer. A little product covers the serum step.
03 / Your routine
Cleanse, apply serum, then moisturize. Keep your existing cream; a matching range is optional.
Inside PDRN Serum
The bottle tells you the headline ingredients. The complete formula tells you how the light serum step is built.
The label's stated Sodium DNA concentration, carried in a lightweight leave-on serum alongside its hydration-supporting base.
The named blend on the bottle. The complete INCI identifies the individual peptides, while the formula's overall use remains a light serum step before cream.
The supporting formula
Ingredient roles describe cosmetic formulation functions, not clinical results for this finished serum. Read the formula facts and complete INCI below.
1.5% applies to PDRN (Sodium DNA). ‘5-Peptide’ is the package's blend name, not a 5% concentration. Individual peptide and supporting ingredient percentages are not stated.
The bottle calls the blend ‘5-Peptide’. The complete INCI lists six peptide names: Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-8, Acetyl Heptapeptide-4, Oligopeptide-1 and Heptapeptide-6. We retain both label records without choosing a subset or inferring blend membership.
The Sodium DNA source is not stated in the materials on file. Salmon-derived and vegan status are unconfirmed. CI 17200 and CI 16035 are included in the original INCI.
General ingredient references: CIR: glycerin · CIR: hyaluronates · CIR: niacinamide. Ingredient information is separate from evidence for this finished product.
The feel / Three application stages
See the application texture in three stages: dispense onto fingertips, spread a thin layer, then let visible pooling settle before cream. The images illustrate the process; they do not measure absorption or skin improvement.
The label directs 3–4 drops onto clean fingertips. The close-up illustrates one droplet, not the full dose.
Press and pat gently, then massage in circular motions. Aim for one even layer.
Let visible wet pooling settle, then moisturize. No fixed waiting time is specified.
Editorial texture illustrations · AI-generated. Feel and finish vary with amount, skin and the products layered afterward.
See the label directions ↗Your daily step
3–4 drops onto fingertips, twice daily. Follow the current package directions; individual reviews may describe a different personal amount.
Begin with clean, dry skin. The label permits use on the face and body; avoid the eyes.
Dispense 3–4 drops onto clean fingertips. Gently press and pat onto the face, then massage in circular motions until absorbed.
Use as the serum step before your usual moisturizer. The package directs twice-daily use.
Apply before moisturizer, then finish with a separate labeled sunscreen. Keep the sunscreen amount consistent when adjusting other layers.
After cleansing, apply your serum layer and follow with moisturizer. Matching PDRN products are optional; use the cream that feels comfortable for your skin.
Patch test before first use. Avoid contact with eyes. Stop use if irritation develops. Read all package warnings below.
A place for every layer
Serum adds a lighter layer; cream fills the moisturizer step. You can keep the products already comfortable in your routine.
Every rating, in the picture
Published feedback for PDRN Serum. Purchase channels and incentive disclosures appear with each review.
Customer rating
5.0 / 53 published reviewsFor this formula. In their own words.
3 matching reviews
Nice formula 2 drops is all I need. I've only used a few times since purchasing but love the formula
Read the full reviewGreat Product - Great Price Only had this serum for a few weeks and am already seeing the beneficial differences! Will purchase again!
Read the full reviewSerum Easy to use. I use it two times a day. Just need two drops each time for the entire face. My skin feels soft and smooth.
Read the full review
The Q-Seal philosophy
We make room for ingredients you can read, a routine you can understand and feedback in customers' own words. PDRN Serum fills one considered role: a lighter hydrating layer before your cream.
The story behind our seal ↗PDRN Serum / 30 mL / 1 fl oz
$19.99
Before you choose
Apply to clean, dry skin before moisturizer. In the morning, finish with a separate labeled sunscreen. A matching cream is optional.
The current package directs 3–4 drops onto fingertips, gentle pressing and patting followed by circular massage, twice daily. Reviews describing two drops reflect an individual's use rather than the label directions.
This is a light serum step. Follow with the moisturizer you normally use. Texture and layering depend on the amount applied and your other products.
1.5% refers only to Sodium DNA. Five-peptide is the blend name on the package. Six peptide names appear in the complete INCI; no subset or individual concentration is inferred. Open Formula facts below for the names.
The current packaging names Sodium DNA but does not state its source. Neither salmon-derived nor vegan status is confirmed in the materials on file.
Open the complete ingredient list and product information below for the current INCI, including colorants, label directions and warnings. Stop use if irritation occurs. The package advises consulting a dermatologist if pregnant or nursing.
Product transparency
Product information verified against current packaging. Last checked September 2026. See our editorial policy for the review method.
Clean and dry the skin on the face and body. Dispense 3-4 drops onto the fingertips. Gently press and pat onto the face, then massage in circular motions until absorbed. Use twice daily.
For external use only. Avoid eyes. Patch test before use. Discontinue if irritation occurs. Consult a dermatologist if pregnant or nursing. Keep out of reach of children.
Additional use caution: Patch test before use and discontinue if irritation occurs.
PDRN source/type: The current packaging identifies Sodium DNA; its source is not stated.
Suitable for: Normal, combination or dehydrated-feeling skin seeking a lightweight serum step beneath moisturizer.
Patch test before broader use. Stop use if irritation develops.
WATER, GLYCERIN, PROPYLENE GLYCOL, ACETYL HEXAPEPTIDE-8, ERYTHRITOL, NIACINAMIDE, SODIUM DNA, SODIUM HYALURONATE, CARBOMER, HYDROXYETHYLCELLULOSE, ARBUTIN, TRIETHANOLAMINE, DIPOTASSIUM GLYCYRRHIZATE, DISODIUM EDTA, PALMITOYL TRIPEPTIDE-1, PALMITOYL TRIPEPTIDE-8, ACETYL HEPTAPEPTIDE-4, OLIGOPEPTIDE-1, HEPTAPEPTIDE-6, ORYZA SATIVA (RICE) EXTRACT, PHRAGMITES COMMUNIS EXTRACT, ZEA MAYS (CORN) SILK EXTRACT, MALVA SYLVESTRIS (MALLOW) FLOWER/LEAF/STEM EXTRACT, ALOE BARBADENSIS EXTRACT, ANGELICA KEISKEI EXTRACT, PHLORETIN, PAEONIA VEITCHII ROOT EXTRACT, PHENOXYETHANOL, ETHYLHEXYLGLYCERIN, STEPHANIA TETRANDRA EXTRACT, TARAXACUM OFFICINALE (DANDELION) LEAF EXTRACT, SAURURUS CHINENSIS LEAF/ROOT EXTRACT, CI 17200, CI 16035.
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