The short answer
Use NAD+ Serum after cleansing and before moisturizer. NAD+ Cream fills the moisturizer step after lighter layers. Both packages direct morning and evening use, but they specify different handling instructions. A matching pair is optional.
Follow the serum label
The current 30 mL NAD+ Serum directions say to take 2–3 drops in the palm after cleansing, morning and evening. Gently press onto the face and neck, then massage from the inside out until absorbed.
The packaging gives a drop amount, not a pump count. Do not treat one pump as a known number of drops. Keep hands clean and use the stated directions rather than copying an individual creator's personal amount.
Follow the cream label
The current 2.13 oz NAD+ Cream directions say to scoop an appropriate amount after cleansing and toning, gently massage onto the face and neck until the capsules melt and are absorbed, and use it morning and night.
An appropriate amount is not a fixed scoop measurement. The label's capsule description explains the application step; it does not establish an encapsulation percentage, release rate or tested delivery advantage.
A short morning routine
- Step 1: Cleanse according to the cleanser's directions.
- Step 2: Apply the label-directed serum step if you use it.
- Step 3: Apply moisturizer where that step is needed.
- Step 4: Finish with a separate labeled sunscreen, following its directions.
The AAD's general product-order guidance places treatment products after cleansing and before moisturizer or sunscreen. Individual product or medical instructions still matter. Neither Neatique NAD+ product has an SPF claim.
A short evening routine
After cleansing, apply the serum if it has a useful place in your routine, then finish with moisturizer. You can use NAD+ Cream alone after its preparation steps or keep a moisturizer you already like after the serum.
When the layers feel heavy or pill
The labels do not prescribe a waiting period between serum and cream. Let the first layer spread evenly, avoid repeated rubbing and simplify the routine if the combined layers feel excessive. Keep sunscreen use consistent while investigating the other layers.
The existing serum and cream routine-order guide explains general texture order and pilling. Use the NAD+ comparison to decide which format fills a missing step.
Frequently asked questions
Do I need the cream if I use the serum
You can keep your usual moisturizer. The matching cream is an option, not a requirement.
How long should I wait
No fixed number of minutes is stated by these packages. Follow the directions and judge whether the layers spread comfortably together.
Can the cream replace sunscreen
No SPF protection is claimed. Use a separate sunscreen in the daytime routine.
Where are the cautions
Each product page contains the complete warnings. Both formulas include fragrance; review the full INCI before introducing them if you avoid particular ingredients.
Editorial note
Prepared with AI research and drafting assistance and approved for publication by Neatique editorial review. Illustrations explain routine roles and label checks; they do not depict clinical results.